Combined FDG-PET and hyperpolarized pyruvate-MRSI (hyperPET) for cancer metabolic phenotyping – a pilot study

Comparison between 8- and 32-channel phased-array receive coils for in vivo hyperpolarized C-13 brain imaging

Considerations for Spin Order Transfer to 13C-labeled pyruvate precursors by Parahydrogen-induced Polarization for in vivo applications

Author:Neil Stewart  Mitsushi Tomohiro  Yoshiki Uchio  Kensuke Takoshima  Shingo Matsumoto  

Author Institution:Hokkaido University  

Session Type:Electronic Poster  

Session Date:Monday, 18 June 2018  

Session Time:16:15  

Session:Hyperpolarisation: Technical Developments  

Program Number:3573  

Presentation Time:

Room Number:Exhibition Hall  

Computer Number:Computer 21  

Developing a Regional Bolus Tracking and Real-time B1 Calibration Method for Hyperpolarized 13C MRI

Author:Shuyu Tang  Eugene Milshteyn  Galen Reed  Jeremy Gordon  Robert Bok  Daniel Vigneron  Peder Larson  

Author Institution:HeartVista  University of California at San Francisco  

Session Type:Electronic Poster  

Session Date:Monday, 18 June 2018  

Session Time:16:15  

Session:Hyperpolarisation: Technical Developments  

Program Number:3555  

Presentation Time:

Room Number:Exhibition Hall  

Computer Number:Computer 3  

The effect of ¹H-decoupling on hyperpolarized ¹³C signal decay – a study on choline chloride analogs and comparison to the effect of deuterium substitution of directly bonded protons

Author:Sivaranjan Uppala  Gamliel Ayelet  Atara Nardi Schreiber  Talia Harris  Jacob Sosna  J. Moshe Gomori  Rachel Katz-Brull  

Author Institution:Hadassah-Hebrew University Medical Center  

Session Type:Electronic Poster  

Session Date:Monday, 18 June 2018  

Session Time:16:15  

Session:Hyperpolarisation: Technical Developments  

Program Number:3557  

Presentation Time:

Room Number:Exhibition Hall  

Computer Number:Computer 5  

Extended Signal Modelling and Regularization for Multi-Echo Hyperpolarized Metabolic Image Reconstruction

Feasibility of Imaging Lung Cancer Using Hyperpolarized MRI Technology

Hyperpolarization without a polarizer: in vivo 13C-MRI using SAMBADENA

Improved Hyperpolarization of Solid and Mesoporous Nanoscale Silicon Particles Using TEMPO Radicals Allows In Vivo 29Si MRI

Author:Nicholas Whiting  Jingzhe Hu  Shivanand Pudakalakatti  Caitlin McCowan  Hyeonglim Seo  Youngbok Lee  Pratip Bhattacharya  

Author Institution:Hanyang University  The University of Texas MD Anderson Cancer Center  

Session Type:Electronic Poster  

Session Date:Monday, 18 June 2018  

Session Time:16:15  

Session:Hyperpolarisation: Technical Developments  

Program Number:3575  

Presentation Time:

Room Number:Exhibition Hall  

Computer Number:Computer 23  

Improved Hyperpolarized Cerebral Perfusion Imaging Using a Sucrose/Water Glassing Matrix for tert-Butanol

Author:Gopal Varma  Patricia Coutinho de Souza  Cody Callahan  David Alsop  Aaron Grant  

Author Institution:Beth Israel Deaconess Medical Center, Harvard Medical School  

Session Type:Electronic Poster  

Session Date:Monday, 18 June 2018  

Session Time:16:15  

Session:Hyperpolarisation: Technical Developments  

Program Number:3570  

Presentation Time:

Room Number:Exhibition Hall  

Computer Number:Computer 18  

Improving robustness of hyperpolarized 13C MRSI using k-t spiral acquisitions

Author:Erin Adamson  Benjamin Cox  Sean Fain  

Author Institution:University of Wisconsin-Madison  

Session Type:Electronic Poster  

Session Date:Monday, 18 June 2018  

Session Time:16:15  

Session:Hyperpolarisation: Technical Developments  

Program Number:3562  

Presentation Time:

Room Number:Exhibition Hall  

Computer Number:Computer 10  

A Late-Stage Deuteration Method for T1 Prolongation and Enhanced In Vivo Signal to Noise Ratio of Hyperpolarized 13C Substrates

Macrocyclic Xenon hosts: potential inhibitors and reporters for protein aggregation in Hyper-CEST MRI

Author:Jan Oliver Jost  Christopher Witte  Leif Schröder  

Author Institution:Leibniz Forschungsinstitut für Molekulare Pharmakologie  

Session Type:Electronic Poster  

Session Date:Monday, 18 June 2018  

Session Time:16:15  

Session:Hyperpolarisation: Technical Developments  

Program Number:3576  

Presentation Time:

Room Number:Exhibition Hall  

Computer Number:Computer 24  

Mitigating Chemical Exchange Effects in Advanced Pulse Sequences for pH Imaging with Hyperpolarized [13C]bicarbonate

Author:David Korenchan  Jeremy Gordon  Sukumar Subramaniam  Renuka Sriram  Peder Larson  Robert Flavell  John Kurhanewicz  

Author Institution:UC San Francisco  

Session Type:Electronic Poster  

Session Date:Monday, 18 June 2018  

Session Time:16:15  

Session:Hyperpolarisation: Technical Developments  

Program Number:3563  

Presentation Time:

Room Number:Exhibition Hall  

Computer Number:Computer 11  

Modeling In Vivo Metabolism of Hyperpolarized Pyruvate in Human Brain Tumor Patients.

Multichannel Hyperpolarized 13C MRI in a Patient with Liver Metastases using Multi-slice EPI and an Alternating Projection Method for Denoising

Author:Rie Hansen  Jeremy Gordon  Peter Shin  Zihan Zhu  Daniele Mammoli  Pamela Munster  Rahul Aggarwal  Michael Ohliger  Peder Larson  Lars Hanson  Jan Ardenkjaer-Larsen  Daniel Vigneron  

Author Institution:Technical University of Denmark  UCSF  

Session Type:Electronic Poster  

Session Date:Monday, 18 June 2018  

Session Time:16:15  

Session:Hyperpolarisation: Technical Developments  

Program Number:3560  

Presentation Time:

Room Number:Exhibition Hall  

Computer Number:Computer 8  

Optimized Single Shot 3D Sequence for High Resolution Hyperpolarized 13C Imaging

Author:Jiazheng Wang  Richard Hesketh  Alan Wright  Kevin Brindle  

Author Institution:University of Cambridge  

Session Type:Electronic Poster  

Session Date:Monday, 18 June 2018  

Session Time:16:15  

Session:Hyperpolarisation: Technical Developments  

Program Number:3559  

Presentation Time:

Room Number:Exhibition Hall  

Computer Number:Computer 7  

Optimizing signal-to-noise ratio for hyperpolarized carbon-13 magnetic resonance imaging using a hybrid flip angle scheme

Author:Lauren Smith  Trevor Wade  Alireza Akbari  Conrad Rockel  Lanette Friesen-Waldner  Charles McKenzie  

Author Institution:Western University  

Session Type:Electronic Poster  

Session Date:Monday, 18 June 2018  

Session Time:16:15  

Session:Hyperpolarisation: Technical Developments  

Program Number:3558  

Presentation Time:

Room Number:Exhibition Hall  

Computer Number:Computer 6  

A perfused heart system to simulate first pass observation of rat cardiac metabolism with hyperpolarized [1-¹³C]pyruvate and determination of LDH flux using selective excitation

Author:Gal Sapir  Talia Harris  Assad Azar  Atara Nardi-Schreiber  Ayelet Gamliel  Jacob Sosna  Moshe Gomori  Rachel Katz-Brull  

Author Institution:Hadassah-Hebrew University Medical Center  

Session Type:Electronic Poster  

Session Date:Monday, 18 June 2018  

Session Time:16:15  

Session:Hyperpolarisation: Technical Developments  

Program Number:3556  

Presentation Time:

Room Number:Exhibition Hall  

Computer Number:Computer 4  

Probing renal pH and aminopeptidase N activity with hyperpolarized [1-13C]alaninamide

Author:Alice Radaelli  Hikari Yoshihara  Ryunosuke Hata  Shinsuke Sando  Rolf Gruetter  

Author Institution:EPFL  Kyushu University  The University of Tokyo  

Session Type:Electronic Poster  

Session Date:Monday, 18 June 2018  

Session Time:16:15  

Session:Hyperpolarisation: Technical Developments  

Program Number:3566  

Presentation Time:

Room Number:Exhibition Hall  

Computer Number:Computer 14  

A robust approach to generate high polarization levels of metabolites within seconds with para-hydrogen

Author:Sergey Korchak  Shengjun Yang  Salvatore Mamone  Stefan Glöggler  

Author Institution:Max-Planck-Institute for Biophysical Chemistry  

Session Type:Electronic Poster  

Session Date:Monday, 18 June 2018  

Session Time:16:15  

Session:Hyperpolarisation: Technical Developments  

Program Number:3571  

Presentation Time:

Room Number:Exhibition Hall  

Computer Number:Computer 19  

Slice Profile Induced Errors in Metabolic Quantification of Hyperpolarized Pyruvate.

Author:Christopher Walker  James Bankson  

Author Institution:MD Anderson Cancer Center  

Session Type:Electronic Poster  

Session Date:Monday, 18 June 2018  

Session Time:16:15  

Session:Hyperpolarisation: Technical Developments  

Program Number:3561  

Presentation Time:

Room Number:Exhibition Hall  

Computer Number:Computer 9  

Spiral-In/Out Multi Spin-Echo Acquisitions for Increased SNR in Dynamic Hyperpolarized 13C MRI

Author:Shuyu Tang  Robert Bok  Eugene Milshteyn  Daniel Vigneron  Peder Larson  

Author Institution:University of California at San Francisco  

Session Type:Electronic Poster  

Session Date:Monday, 18 June 2018  

Session Time:16:15  

Session:Hyperpolarisation: Technical Developments  

Program Number:3554  

Presentation Time:

Room Number:Exhibition Hall  

Computer Number:Computer 2  

Susceptibility-Induced Distortion Correction in Hyperpolarized Echo Planar Imaging

Author:Jack Miller  Angus Lau  Damian Tyler  

Author Institution:University of Oxford  

Session Type:Electronic Poster  

Session Date:Monday, 18 June 2018  

Session Time:16:15  

Session:Hyperpolarisation: Technical Developments  

Program Number:3567  

Presentation Time:

Room Number:Exhibition Hall  

Computer Number:Computer 15